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Article

Prenatal genotyping of Jk(a) and Jk(b) of the human Kidd blood group system by allele-specific polymerase chain reaction.

Prenatal diagnosis - 1 Dec 1998

Hessner M J, Pircon R A, Johnson S T, Luhm R A

Abstract excerpt

An allele-specific polymerase chain reaction (ASPCR) assay for prenatal genotyping of the Kidd antigen system in order to identify pregnancies at risk for haemolytic disease of the newborn (HDN) was developed. Oligonucleotide primers were designed for ASPCR of JKA and JKB. A validation study was performed using DNA isolated from 54 serotyped whole blood samples and 8 amniocentesis samples. A concordance rate of...

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PMID: 9885013
DOI: 10.1002/(sici)1097-0223(199812)18:12<1225::aid-pd434>3.0.co;2-d

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