Article
Cell-Free DNA Analysis for the Determination of Fetal Red Blood Cell Antigen Genotype in Individuals With Alloimmunized Pregnancies.
Obstetrics and gynecology - 1 Oct 2024
Rego Shannon, Ashimi Balogun Olaide, Emanuel Kirsten, Overcash Rachael, Gonzalez Juan M, Denomme Gregory A, Hoskovec Jennifer, King Haley, Wilson Ashley, Wynn Julia, Moise Kenneth J
Abstract excerpt
OBJECTIVE: To evaluate the accuracy of next-generation sequencing-based quantitative cell-free DNA analysis for fetal antigen genotyping in individuals with alloimmunized pregnancies undergoing clinical testing in practices across the United States as early as 10 weeks of gestation, with the objective of identifying individuals with pregnancies at risk for hemolytic disease of the fetus and newborn and guiding...
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