Article
Ellipse mutations in the Drosophila homologue of the EGF receptor affect pattern formation, cell division, and cell death in eye imaginal discs.
Developmental biology - 1 Apr 1992
Baker N E, Rubin G M
Abstract excerpt
Ellipse alleles are mutations of the EGF-receptor homologue that reduce the number of ommatidia in the eye imaginal disc. Cobalt sulfide staining, expression of hairy and scabrous proteins, and mosaic analysis indicated that Elp mutations affect ommatidial precluster formation in the morphogenetic furrow. BrdU incorporation studies suggest that cells diverted from precluster formation instead enter S-phase after...
Topics
- Alleles
- Animals
- Cell Death
- Cell Differentiation
- Cell Division
- Drosophila
- Embryo, Nonmammalian
- ErbB Receptors
- Eye
- Genes, Recessive
- Morphogenesis
- Mutation