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Article

Echinoid limits R8 photoreceptor specification by inhibiting inappropriate EGF receptor signalling within R8 equivalence groups.

Development (Cambridge, England) - 1 Aug 2003

Rawlins Emma L, White Neil M, Jarman Andrew P

Abstract excerpt

EGF receptor signalling plays diverse inductive roles during development. To achieve this, its activity must be carefully regulated in a variety of ways to control the time, pattern, intensity and duration of signalling. We show that the cell surface protein Echinoid is required to moderate Egfr signalling during R8 photoreceptor selection by the proneural gene atonal during Drosophila eye development. In...

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Identifiers

PMID: 12835388
DOI: 10.1242/dev.00602

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Echinoid limits R8 photoreceptor specification by inhibiting inappropriate EGF receptor signalling within R8 equivalence groups.PMID 12835388Read ↗

The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway.Semantic proximity Read ↗

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Evolution of proneural atonal expression during distinct regulatory phases in the developing Drosophila eye.Semantic proximity Read ↗

Analysis of transient hypermorphic activity of E(spl)D during R8 specification.Semantic proximity Read ↗

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