Article
Transmission disequilibrium of maternally-inherited CTLA-4 microsatellite alleles in idiopathic recurrent miscarriage.
Journal of reproductive immunology - 1 Nov 1998
Tsai A F, Kaufman K A, Walker M A, Karrison T G, Odem R R, Barnes R B, Scott J R, Schreiber J R, Stephenson M D, Ober C
Abstract excerpt
To elucidate the mechanisms that facilitate tolerance at the maternal-fetal interface, we are investigating the role of genes that are involved in peripheral self-tolerance in couples with idiopathic recurrent miscarriage. CTLA-4 is a negative regulator of T-cell proliferation and has been associ...
Topics
- Abatacept
- Abortion, Habitual
- Adult
- Alleles
- Antigens, CD
- Antigens, Differentiation
- CTLA-4 Antigen
- Female
- Genotype
- Humans
- Immunoconjugates
- Infant, Newborn
