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Article

Bergmann glia require continuous association with Purkinje cells for normal phenotype expression.

Glia - 1 Jul 1993

Fisher M, Trimmer P, Ruthel G

Abstract excerpt

Bergmann glia (Bg) respond to the early postnatal Purkinje cell (Pc) death in Lurcher (Lc) mutant mouse cerebellum by down-regulating expression of the enzyme glycerol-3-phosphate dehydrogenase (GPDH). To determine whether glial GPDH expression requires the continued presence of Pcs in adults, we used single intracerebellar injections of kainic acid to kill Pcs in wild-type mice from 7 weeks to 11 months old. Bg...

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Identifiers

PMID: 8225559
DOI: 10.1002/glia.440080305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Bergmann glia require continuous association with Purkinje cells for normal phenotype expression.PMID 8225559Read ↗

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