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Selective hippocampal lesions differentially affect the phenotypic fate of transplanted neuronal precursor cells.

Experimental neurology - 1 May 1996

Shihabuddin L S, Holets V R, Whittemore S R

Abstract excerpt

RN33B cells, a CNS-derived neuronal precursor cell line, transplanted into normal adult rat hippocampus can survive and morphologically differentiate with their ultimate morphology dependent on the integration site. This study examined the differentiation and structural integration of RN33B cells transplanted into the lesioned adult hippocampus. Pyramidal neurons of the CA1-3 regions or granular neurons in the...

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PMID: 8635569
DOI: 10.1006/exnr.1996.0081

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