Article
Impaired development of the cerebellum in transgenic mice expressing the immediate-early protein IE180 of pseudorabies virus.
Virology - 15 Mar 2003
Taharaguchi Satoshi, Kon Yasuhiro, Yoshino Saori, Ono Etsuro
Abstract excerpt
Pseudorabies virus (PRV) infection in animals other than its natural host almost always gives rise to fatal diseases in the central nervous system as a result of infection of peripheral neurons and subsequently to the brain. PRV immediate-early protein (IE180) activates transcription of the PRV early and late genes, and other viral and cellular genes, and represses its own transcription. To examine specific...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
