Article
Two common polymorphisms in the coding part of the CD43 gene are not associated with atopy.
International archives of allergy and immunology - 1 Dec 1998
Kruse S, Kuehr J, Forster J, Deichmann K A
Abstract excerpt
BACKGROUND: Recently linkage and association of the chromosomal region 16p12-11 with enhanced IgE responsiveness have been shown. The gene coding for CD43 (sialophorin) has been localized to this region. Sialophorin represents a major sialoglycoprotein on the surface of human lymphocytes, monocytes and granulocytes. It is supposed to play an important role in human mast cell, T- and B-cell regulation and...
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