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Article

Common polymorphisms in the CTLA-4 and CD28 genes at 2q33 are not associated with asthma or atopy.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 2000

Heinzmann A, Plesnar C, Kuehr J, Forster J, Deichmann K A

Abstract excerpt

Recently, genetic linkage of the chromosomal region 2q33 with asthma has been shown. The genes coding for CD28 and CTLA-4 have been localized to this chromosomal region. CD28 and CTLA-4 have been shown to be involved as an important costimulatory signal in the regulation of allergic inflammation and TH2 cytokine production, and thus both genes are good candidate genes for asthma and atopy. Two common...

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Source

Identifiers

PMID: 10792419
DOI: 10.1046/j.1365-2370.2000.00198.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Common polymorphisms in the CTLA-4 and CD28 genes at 2q33 are not associated with asthma or atopy.PMID 10792419Read ↗

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