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Article

A life cycle alteration can correct molting defects in Caenorhabditis elegans.

Developmental biology - 1 Mar 2022

Binti Shaonil, Melinda Rosa V, Joseph Braveen B, Edeen Phillip T, Miller Sam D, Fay David S

Abstract excerpt

Molting is a widespread feature in the development of many invertebrates, including nematodes and arthropods. In Caenorhabditis elegans, the highly conserved protein kinases NEKL-2/NEK8/9 and NEKL-3/NEK6/7 (NEKLs) promote molting through their involvement in the uptake and intracellular trafficking of epidermal cargos. We found that the relative requirements for NEKL-2 and NEKL-3 differed at different life-cycle...

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Source

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Identifiers

PMID: 35038442
DOI: 10.1016/j.ydbio.2022.01.001
PMCID: PMC8867747

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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