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Article

Opposing roles for lipocalins and a CD36 family scavenger receptor in apical extracellular matrix-dependent protection of narrow tube integrity.

Development (Cambridge, England) - 15 Aug 2026

Belfi Alexandra C, Aviles Sage G, Forman-Rubinsky Rachel, Gill Hasreet K, Cohen Jennifer D, Nawrocka Aleksandra, Bourez Axelle, van Antwerpen Pierre, Laurent Patrick, Sundaram Meera V

Abstract excerpt

All exposed epithelial surfaces, including the walls of internal tubes, are lined by a lipid and glycoprotein-rich apical extracellular matrix (aECM) that helps shape and protect the apical domain. Secreted lipocalins are lipid transporters frequently found within apical compartments. We show that loss of the Caenorhabditis elegans lipocalin LPR-1 disrupts the assembly of another lipocalin, LPR-3, within the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41294099
DOI: 10.1242/dev.205309
PMCID: PMC12848578

Genes

CD36

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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