A region of the Sir1 protein dedicated to recognition of a silencer and required for interaction with the Orc1 protein in saccharomyces cerevisiae.

doi:10.1093/genetics/151.1.31

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Article

A region of the Sir1 protein dedicated to recognition of a silencer and required for interaction with the Orc1 protein in saccharomyces cerevisiae.

Genetics - 1 Jan 1999

Gardner K A, Rine J, Fox C A

Abstract excerpt

Silencing of the cryptic mating-type loci HMR and HML requires the recognition of DNA sequence elements called silencers by the Sir1p, one of four proteins dedicated to the assembly of silenced chromatin in Saccharomyces cerevisiae. The Sir1p is thought to recognize silencers indirectly through i...

Topics

Alleles
Animals
DNA-Binding Proteins
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Recessive
Genes, Regulator
Mutation, Missense
Origin Recognition Complex
Plasmids
Rabbits
Recombinant Fusion Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Silent Information Regulator Proteins, Saccharomyces cerevisiae

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Identifiers

PMID: 9872946
DOI: 10.1093/genetics/151.1.31
PMCID: PMC1460464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9872946-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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