Article
Inhibition of colicin synthesis by the antibiotic globomycin.
Archives of microbiology - 1 Dec 1998
Cavard D
Abstract excerpt
The antibiotic globomycin, an inhibitor of LspA (the lipoprotein signal peptidase), inhibited synthesis of colicin by Escherichia coli cells grown in rich medium. This inhibition was stronger in cells with mutation(s) within either the colicin operon, which is located on a plasmid, or the host ch...
Topics
- Anti-Bacterial Agents
- Blotting, Western
- Colicins
- Culture Media
- Electrophoresis, Polyacrylamide Gel
- Escherichia coli
- Genes, Bacterial
- Hot Temperature
- Lipoproteins
- Mutation
- Operon
- Peptides
- Phenotype
- Sodium Azide
- Transcription, Genetic