Article
Interference with murein turnover has no effect on growth but reduces beta-lactamase induction in Escherichia coli.
Journal of bacteriology - 1 Dec 1999
Kraft A R, Prabhu J, Ursinus A, Höltje J V
Abstract excerpt
Physiological studies of a mutant of Escherichia coli lacking the three lytic transglycosylases Slt70, MltA, and MltB revealed that interference with murein turnover can prevent AmpC beta-lactamase induction. The triple mutant, although growing normally, shows a dramatically reduced rate of murein turnover. Despite the reduction in the formation of low-molecular-weight murein turnover products, neither the rate...
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