Article
Induction of beta-lactamase in Gram-negative bacteria.
Diagnostic microbiology and infectious disease - 1 Jan 2000
Wiedemann B, Peter K
Abstract excerpt
The induction of beta-lactamase in Gram-negative bacteria in vitro has been established. It is possible to distinguish between high and low beta-lactamase inducers in vitro. This differentiation is clinically irrelevant because induction has little effect on the treatment of a bacterial infection with beta-lactam antibiotics. Regardless of the amount of induced beta-lactamase, the kill kinetics are usually not...
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