Article
The murG gene of Escherichia coli codes for the UDP-N-acetylglucosamine: N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase involved in the membrane steps of peptidoglycan synthesis.
Journal of bacteriology - 1 Aug 1991
Mengin-Lecreulx D, Texier L, Rousseau M, van Heijenoort J
Abstract excerpt
Physiological properties of the murG gene product of Escherichia coli were investigated. The inactivation of the murG gene rapidly inhibits peptidoglycan synthesis in exponentially growing cells. As a result, various alterations of cell shape are observed, and cell lysis finally occurs when the p...
Topics
- Amino Acid Sequence
- Bacterial Outer Membrane Proteins
- Cell Membrane
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Glucosyltransferases
- Glycolipids
- Molecular Sequence Data
- Molecular Weight
- Mutation
- N-Acetylglucosaminyltransferases
- Peptidoglycan