Article
Regulating colicin synthesis to cope with stress and lethality of colicin production.
Biochemical Society transactions - 1 Dec 2012
Žgur-Bertok Darja
Abstract excerpt
Colicins are plasmid-encoded bacteriocins active against Escherichia coli and closely related species of Enterobacteriaceae. They promote microbial diversity and genetic diversity in E. coli populations. Colicin synthesis is characteristically repressed by the LexA protein, the key regulator of the SOS response. As colicins are released by cell lysis, generally two LexA dimers binding to two overlapping SOS boxes...
Topics
- Bacterial Proteins
- Colicins
- Escherichia coli
- Escherichia coli Proteins
- Gene Expression Regulation, Bacterial
- Genetic Variation
- Multigene Family
- Operon
- SOS Response, Genetics
- Serine Endopeptidases
- Stress, Physiological
- Transcription, Genetic
