Article
[Studies of small GTPase Rab7 association with endosomes of cells expressing normal and mutant forms of epidermal growth factor receptors].
Tsitologiia - 1 Jan 1998
Sokolova I P, Arnautov A M, Nikol'skiĭ N N, Kornilova E S
Abstract excerpt
A study was made of an association of small GTPase Rab7, commonly considered as a marker of late endosomes, with endosomal compartments of cells expressing EGF receptor with different ability to be sorted for degradative pathway. It was found that in cells HER14, expressing normal EGF receptor, R...
Topics
- 3T3 Cells
- Animals
- Centrifugation, Density Gradient
- Colloids
- Endosomes
- ErbB Receptors
- GTP Phosphohydrolases
- GTP-Binding Proteins
- Mice
- Mutation
- Phosphorylation
- Povidone
- Silicon Dioxide
- rab GTP-Binding Proteins
- rab7 GTP-Binding Proteins
