[Studies of small GTPase Rab7 association with endosomes of cells expressing normal and mutant forms of epidermal growth factor receptors].

Abstract excerpt

A study was made of an association of small GTPase Rab7, commonly considered as a marker of late endosomes, with endosomal compartments of cells expressing EGF receptor with different ability to be sorted for degradative pathway. It was found that in cells HER14, expressing normal EGF receptor, Rab7 was associated with both early and late endosomes and the extent of association correlated with the number of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to 3T3 Cells
• Share to ErbB Receptors
• Share to EGF gene