Article
Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse.
Infection and immunity - 1 Jan 1999
Shea J E, Beuzon C R, Gleeson C, Mundy R, Holden D W
Abstract excerpt
We have investigated the in vivo growth kinetics of a Salmonella typhimurium strain (P11D10) carrying a mutation in ssaJ, a Salmonella pathogenicity island 2 (SPI2) gene encoding a component of a type III secretion system required for systemic growth in mice. Similar numbers of mutant and wild-type cells were recovered from the spleens and livers of BALB/c mice up to 8 h after inoculation by the intraperitoneal...
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