Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse.

doi:10.1128/IAI.67.1.213-219.1999

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Article

Influence of the Salmonella typhimurium pathogenicity island 2 type III secretion system on bacterial growth in the mouse.

Infection and immunity - 1 Jan 1999

Shea J E, Beuzon C R, Gleeson C, Mundy R, Holden D W

Abstract excerpt

We have investigated the in vivo growth kinetics of a Salmonella typhimurium strain (P11D10) carrying a mutation in ssaJ, a Salmonella pathogenicity island 2 (SPI2) gene encoding a component of a type III secretion system required for systemic growth in mice. Similar numbers of mutant and wild-ty...

Topics

Animals
Female
Genes, Bacterial
Kinetics
Liver
Mice
Mice, Inbred BALB C
Mice, Inbred C3H
Mutation
Plasmids
Salmonella Infections, Animal
Salmonella typhimurium
Spleen
Virulence

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