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Article

Identification of a pathogenicity island required for Salmonella survival in host cells.

Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 1996

Ochman H, Soncini F C, Solomon F, Groisman E A

Abstract excerpt

We have identified a region unique to the Salmonella typhimurium chromosome that is essential for virulence in mice. This region harbors at least three genes: two (spiA and spiB) encode products that are similar to proteins found in type III secretion systems, and a third (spiR) encodes a putative regulator. A strain with a mutation in spiA was unable to survive within macrophages but displayed wild-type levels...

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Identifiers

PMID: 8755556
DOI: 10.1073/pnas.93.15.7800
PMCID: PMC38828

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Identification of a pathogenicity island required for Salmonella survival in host cells.PMID 8755556Read ↗

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