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Identification of a pathogenicity island required for Salmonella survival in host cells.

Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 1996

Ochman H, Soncini F C, Solomon F, Groisman E A

Abstract excerpt

We have identified a region unique to the Salmonella typhimurium chromosome that is essential for virulence in mice. This region harbors at least three genes: two (spiA and spiB) encode products that are similar to proteins found in type III secretion systems, and a third (spiR) encodes a putativ...

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Mutation
Molecular Sequence Data
Amino Acid Sequence
Mice
Cell Line
Bacterial Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Bacterial

Sequence Homology, Amino Acid

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Identifiers

PMID: 8755556
DOI: 10.1073/pnas.93.15.7800
PMCID: PMC38828

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-8755556-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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Identification of a pathogenicity island required for Salmonella survival in host cells.PMID 8755556Read ↗

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The Salmonella Pathogenicity Island (SPI) 1 contributes more than SPI2 to the colonization of the chicken by Salmonella enterica serovar Typhimurium.Semantic proximity Read ↗

Salmonella pathogenicity islands encoding type III secretion systems.Semantic proximity Read ↗

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Salmonella typhimurium virulence genes are induced upon bacterial invasion into phagocytic and nonphagocytic cells.Semantic proximity Read ↗

Characterization of the mutS-proximal region of the Salmonella typhimurium SPI-1 identifies a group of pathogenicity island-associated genes.Semantic proximity Read ↗

SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells.Semantic proximity Read ↗

SlyA regulates function of Salmonella pathogenicity island 2 (SPI-2) and expression of SPI-2-associated genes.Semantic proximity Read ↗

Identification and characterization of mutants with increased expression of hilA, the invasion gene transcriptional activator of Salmonella typhimurium.Semantic proximity Read ↗

SpiC is required for translocation of Salmonella pathogenicity island 2 effectors and secretion of translocon proteins SseB and SseC.Semantic proximity Read ↗

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