Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells.

Microbes and infection - 1 Jun 2003

Coombes Brian K, Brown Nat F, Kujat-Choy Sonya, Vallance Bruce A, Finlay B Brett

Abstract excerpt

The Salmonella pathogenicity island-2 (SPI2) is a virulence locus on the bacterial chromosome required for intracellular proliferation and systemic infection in mice. Cell culture models and a murine model of systemic infection were used to address the role of an uncharacterized SPI2 open reading frame, designated as sseA, in Salmonella virulence. A Salmonella strain with an unmarked internal deletion of sseA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, Bacterial
Share to HeLa Cells
Share to Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Chaperones

Share to Protein Transport

Share to Salmonella

Share to Salmonella Infections, Animal

Share to Virulence Factors

Source

Identifiers

PMID: 12787732
DOI: 10.1016/s1286-4579(03)00094-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells.PMID 12787732Read ↗

SsaM and SpiC interact and regulate secretion of Salmonella pathogenicity island 2 type III secretion system effectors and translocators.Semantic proximity Read ↗

SpiC is required for translocation of Salmonella pathogenicity island 2 effectors and secretion of translocon proteins SseB and SseC.Semantic proximity Read ↗

SseA is a chaperone for the SseB and SseD translocon components of the Salmonella pathogenicity-island-2-encoded type III secretion system.Semantic proximity Read ↗

Functions and effectors of the Salmonella pathogenicity island 2 type III secretion system.Semantic proximity Read ↗

The SPI2-encoded SseA chaperone has discrete domains required for SseB stabilization and export, and binds within the C-terminus of SseB and SseD.Semantic proximity Read ↗

Functions of the Salmonella pathogenicity island 2 (SPI-2) type III secretion system effectorsSemantic proximity Read ↗

Salmonella pathogenicity islands encoding type III secretion systems.Semantic proximity Read ↗

Functional dissection of SseF, a membrane-integral effector protein of intracellular Salmonella enterica.Semantic proximity Read ↗

Functional transfer of Salmonella pathogenicity island 2 to Salmonella bongori and Escherichia coli.Semantic proximity Read ↗

SlyA regulates function of Salmonella pathogenicity island 2 (SPI-2) and expression of SPI-2-associated genes.Semantic proximity Read ↗

Effector proteins encoded by Salmonella pathogenicity island 2 interfere with the microtubule cytoskeleton after translocation into host cells.Semantic proximity Read ↗

<i>Salmonella</i> Pathogenicity Island 2Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.