Article
Selective vertical transmission of HIV-1 antiretroviral resistance mutations.
AIDS (London, England) - 3 Dec 1998
Colgrove R C, Pitt J, Chung P H, Welles S L, Japour A J
Abstract excerpt
OBJECTIVE: To examine the patterns of vertical transmission of zidovudine (ZDV) resistance mutations. DESIGN: HIV-1 reverse transcriptase codons 10-250 were sequenced from 24 pairs of ZDV-exposed women and their HIV-infected infants as part of the Women and Infants Transmission Study. METHODS: Vi...
Topics
- Anti-HIV Agents
- Base Sequence
- DNA, Viral
- Drug Resistance, Microbial
- Female
- Genotype
- HIV Infections
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Infant, Newborn
- Infectious Disease Transmission, Vertical
- Molecular Sequence Data
- Mutation
- Reverse Transcriptase Inhibitors
- Zidovudine