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Article

Selective vertical transmission of HIV-1 antiretroviral resistance mutations.

AIDS (London, England) - 3 Dec 1998

Colgrove R C, Pitt J, Chung P H, Welles S L, Japour A J

Abstract excerpt

OBJECTIVE: To examine the patterns of vertical transmission of zidovudine (ZDV) resistance mutations. DESIGN: HIV-1 reverse transcriptase codons 10-250 were sequenced from 24 pairs of ZDV-exposed women and their HIV-infected infants as part of the Women and Infants Transmission Study. METHODS: Viral RNA was extracted from tissue culture supernatants and sequenced using fluorescent dye-primer chemistry and an...

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Identifiers

PMID: 9863870
DOI: 10.1097/00002030-199817000-00009

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