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Article

Vertical transmission of multidrug-resistant human immunodeficiency virus type 1 (HIV-1) and continued evolution of drug resistance in an HIV-1-infected infant.

The Journal of infectious diseases - 1 Jun 2001

Johnson V A, Petropoulos C J, Woods C R, Hazelwood J D, Parkin N T, Hamilton C D, Fiscus S A

Abstract excerpt

To confirm the vertical transmission of multidrug-resistant (MDR) human immunodeficiency virus type 1 (HIV-1) and to assess its impact on further evolution of drug-resistant virus in an infant, proviral DNA amplified from infected peripheral blood mononuclear cell cultures was sequenced to identify reverse transcriptase (RT) and protease (PR) mutations. The infant had proviral DNA with evidence of RT mutations...

Read the complete abstract on PubMed

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Share to Drug Resistance, Multiple
Share to HIV Protease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Infectious Disease Transmission, Vertical

Share to Pregnancy Complications, Infectious

Share to Protease Inhibitors

Share to Proviruses

Share to Ritonavir

Share to Zidovudine

Source

Identifiers

PMID: 11343221
DOI: 10.1086/320697

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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