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Article

Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins.

Proceedings of the National Academy of Sciences of the United States of America - 22 Dec 1998

Bardwell L, Cook J G, Zhu-Shimoni J X, Voora D, Thorner J

Abstract excerpt

Kss1, a yeast mitogen-activated protein kinase (MAPK), in its unphosphorylated (unactivated) state binds directly to and represses Ste12, a transcription factor necessary for expression of genes whose promoters contain filamentous response elements (FREs) and genes whose promoters contain pheromone response elements (PREs). Herein we show that two nuclear proteins, Dig1 and Dig2, are required cofactors in...

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Identifiers

PMID: 9860980
DOI: 10.1073/pnas.95.26.15400
PMCID: PMC28054

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Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins.PMID 9860980Read ↗

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