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Article

Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12.

Nature - 9 Jan 2003

Nelson Chris, Goto Susan, Lund Karen, Hung Wesley, Sadowski Ivan

Abstract excerpt

The budding yeast Saccharomyces cerevisiae differentiates into filamentous invasively growing forms under conditions of nutrient limitation. This response is dependent on the transcription factor Ste12 and on the mating pheromone-response mitogen-activated protein (MAP) kinase cascade, but a mechanism for regulation of Ste12 by nutrient limitation has not been defined. Here we show that Ste12 function in...

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PMID: 12520306
DOI: 10.1038/nature01243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Srb10/Cdk8 regulates yeast filamentous growth by phosphorylating the transcription factor Ste12.PMID 12520306Read ↗

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