Article
Loss of LKLF function results in embryonic lethality in mice.
Transgenic research - 1 Jul 1998
Wani M A, Means R T, Lingrel J B
Abstract excerpt
Lung Kruppel-like factor (LKLF) is a member of the Kruppel-like family of zinc finger transcription factors and is closely related to erythroid kruppel-like factor (EKLF), which is necessary for beta-globin gene expression. While EKLF is expressed exclusively in erythroid cells, LKLF is expressed...
Topics
- Animals
- Base Sequence
- DNA Primers
- DNA-Binding Proteins
- Embryonic and Fetal Development
- Erythroid-Specific DNA-Binding Factors
- Female
- Fetal Death
- GATA1 Transcription Factor
- GATA3 Transcription Factor
- Gene Expression Regulation, Developmental
- Gene Targeting
- Hematopoiesis
- Kruppel-Like Transcription Factors
- Lung
- Mice
- Mice, Inbred C57BL
- Mice, Knockout