Article
Recycling cell surface glycoproteins undergo limited oligosaccharide reprocessing in LEC1 mutant Chinese hamster ovary cells.
Glycobiology - 1 Dec 1998
Reichner J S, Helgemo S L, Hart G W
Abstract excerpt
The ability of particular cell surface glycoproteins to recycle and become exposed to individual Golgi enzymes has been demonstrated. This study was designed to determine whether endocytic trafficking includes significant reentry into the overall oligosaccharide processing pathway. The Lec1 mutan...
Topics
- Acetylglucosamine
- Amines
- Animals
- CHO Cells
- Cricetinae
- Endocytosis
- Enzyme Inhibitors
- Golgi Apparatus
- Kinetics
- Mannosidases
- Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase
- Membrane Glycoproteins
- Mutation
- N-Acetylglucosaminyltransferases
- Oligosaccharides
- Phenotype
- Swine