Article
Evidence for core 2 to core 1 O-glycan remodeling during the recycling of MUC1.
Glycobiology - 1 Aug 2013
Razawi Hanieh, Kinlough Carol L, Staubach Simon, Poland Paul A, Rbaibi Youssef, Weisz Ora A, Hughey Rebecca P, Hanisch Franz-Georg
Abstract excerpt
The apical transmembrane glycoprotein MUC1 is endocytosed to recycle through the trans-Golgi network (TGN) or Golgi complex to the plasma membrane. We followed the hypothesis that not only the known follow-up sialylation of MUC1 in the TGN is associated with this process, but also a remodeling of O-glycan core structures, which would explain the previously described differential core 2- vs core 1-based...
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