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Article

Cell surface counter receptors are essential components of the unconventional export machinery of galectin-1.

The Journal of cell biology - 24 Oct 2005

Seelenmeyer Claudia, Wegehingel Sabine, Tews Ivo, Künzler Markus, Aebi Markus, Nickel Walter

Abstract excerpt

Galectin-1 is a component of the extracellular matrix as well as a ligand of cell surface counter receptors such as beta-galactoside-containing glycolipids, however, the molecular mechanism of galectin-1 secretion has remained elusive. Based on a nonbiased screen for galectin-1 export mutants we have identified 26 single amino acid changes that cause a defect of both export and binding to counter receptors. When...

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Identifiers

PMID: 16247033
DOI: 10.1083/jcb.200506026
PMCID: PMC2171196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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