Article
Prevalence of Factor V Genetic Variants Associated With Indian APCR Contributing to Thrombotic Risk.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Sept 2017
Sharma Amit, Bhakuni Teena, Biswas Arijit, Ranjan Ravi, Kumar Ravi, Kishore Kamal, Mahapatra Manoranjan, Jairajpuri Mohamad Aman, Saxena Renu
Abstract excerpt
Phenotypic resistance to activated protein C (APC) is a complex mechanism associated with increased thrombosis risk. Activated protein C resistance (APCR) is mainly influenced by FVLeiden mutation, and various other single nucleotide polymorphisms (SNPs) in FV gene are known to be associated with APCR. The aim of present study was to investigate the incidence and assess possible mechanisms of APCR in Indian...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
