Article
NRAMP1 polymorphism and viral factors in Sardinian multiple sclerosis patients.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Sept 2008
Gazouli Maria, Sechi Leonardo, Paccagnini Daniela, Sotgiu Stefano, Arru Giannina, Nasioulas George, Vassilopoulos Dimitrios
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is believed to be an autoimmune disease occurring in genetically predisposed individuals after an appropriate environmental exposure such as viral infections. Recent studies suggest a significant association between MS and the functional 5'-(GT)n polymorphism in the promoter region of the NRAMP1 gene. In the present study we aimed to evaluate the contribution of the allelic...
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