Article
IFN-γ and TNF-α Gene Polymorphisms in Multiple Sclerosis Patients in Northwest Iran.
Endocrine, metabolic & immune disorders drug targets - 1 Jan 2021
Asgharzadeh Mohammad, Najafi-Ghalehlou Nima, Poor Behroz M, Asgharzadeh Vahid, Pourostadi Mahya, Vegari Ali, Kafil Hossein S, Fadaee Manouchehr, Farhoudi Mehdi, Rashedi Jalil
Abstract excerpt
BACKGROUND: Cytokines are polypeptides that play critical roles in immune responses. Gene polymorphisms occurring in the inflammatory cytokines are taking a role in autoimmune diseases, including multiple sclerosis (MS), which may induce inappropriate immune responses. OBJECTIVE: The aim of this study was to investigate the allelic and genotypic frequencies of interferon gamma gene (IFN-γ) at +874A/T locus and...
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