Article
Notchless encodes a novel WD40-repeat-containing protein that modulates Notch signaling activity.
The EMBO journal - 15 Dec 1998
Royet J, Bouwmeester T, Cohen S M
Abstract excerpt
Signaling by Notch family receptors is involved in many cell-fate decisions during development. Several modifiers of Notch activity have been identified, suggesting that regulation of Notch signaling is complex. In a genetic screen for modifiers of Notch activity, we identified a gene encoding a...
Topics
- Amino Acid Sequence
- Animals
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Genes, Insect
- Head
- Insect Proteins
- Membrane Proteins
- Molecular Sequence Data
- Mutation
- Receptors, Notch
- Repetitive Sequences, Amino Acid
- Sequence Homology, Amino Acid
- Signal Transduction
- Suppression, Genetic
- Thorax
- Wings, Animal