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Article

Mutation, sequence analysis, and association studies of alpha-synuclein in Parkinson's disease.

Neurology - 1 Dec 1998

Parsian A, Racette B, Zhang Z H, Chakraverty S, Rundle M, Goate A, Perlmutter J S

Abstract excerpt

A mutation within the alpha-synuclein gene on human chromosome 4 has been reported to segregate with PD in an Italian family. We screened a sample of familial cases of PD for mutation in the alpha-synuclein gene. None of the familial cases of PD carried a mutation within the alpha-synuclein gene,...

Topics

Aged
Alleles
Chromosomes, Human, Pair 4
DNA Mutational Analysis
Family Health
Female
Humans
Italy
Male
Middle Aged
Nerve Tissue Proteins
Parkinson Disease
Phosphoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Point Mutation

Polymorphism, Genetic

Synucleins

alpha-Synuclein

Source

Identifiers

PMID: 9855543
DOI: 10.1212/wnl.51.6.1757

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9855543-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Mutation, sequence analysis, and association studies of alpha-synuclein in Parkinson's disease.PMID 9855543Read ↗

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