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The extracellular matrix as a multitasking player in disease

25 Mar 2019

Abstract excerpt

Extracellular matrices (ECMs) are highly specialized and dynamic three-dimensional (3D) scaffolds into which cells reside in tissues. ECM is composed of a variety of fibrillar components, such as collagens, fibronectin, and elastin, and non-fibrillar molecules as proteoglycans, hyaluronan, and glycoproteins including matricellular proteins. These macromolecular components are interconnected forming complex...

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PMID: 30908868
DOI: 10.1111/febs.14818

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