Article
Mitochondrial DNA rearrangements, including partial duplications, occur in young and old rat tissues.
Mutation research - 3 Nov 1998
Moore C A, Gudikote J, Van Tuyle G C
Abstract excerpt
Using polymerase chain reaction (PCR) with back-to-back primers, 85 different mitochondrial DNA (mtDNA) rearrangements, consisting of partial duplications or mini-circles, were detected in brain, liver, and heart tissue from Fischer 344 rats. The regions around the mitochondrial tRNALeu(UUR) gene, the cluster of three tRNA genes [His, Ser(AGY), Leu(UUC)], as well as the region of the displacement loop were...
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