Mitochondrial D-loop sequences are integrated in the rat nuclear genome.

Abstract excerpt

We have cloned two fragments of rat nuclear DNA (nucDNA), 3.3 x 10(3) nucleotide-pairs (knp) and 9.1 knp, that contain a 0.5 knp section sharing 80% sequence identity with the mitochondrial DNA (mtDNA) heavy strand origin of replication (D-loop) nascent strand and 88% identity with each other. The light and heavy strand promoters of the D-loop region are not present in either clone, thus they likely do not...

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