Mitochondrial D-loop sequences are integrated in the rat nuclear genome.

Article

Mitochondrial D-loop sequences are integrated in the rat nuclear genome.

Journal of molecular biology - 20 Oct 1991

Zullo S, Sieu L C, Slightom J L, Hadler H I, Eisenstadt J M

Abstract excerpt

We have cloned two fragments of rat nuclear DNA (nucDNA), 3.3 x 10(3) nucleotide-pairs (knp) and 9.1 knp, that contain a 0.5 knp section sharing 80% sequence identity with the mitochondrial DNA (mtDNA) heavy strand origin of replication (D-loop) nascent strand and 88% identity with each other. The light and heavy strand promoters of the D-loop region are not present in either clone, thus they likely do not...

Topics

Amino Acid Sequence
Animals
Base Sequence
Blotting, Southern
Cell Nucleus
Cloning, Molecular
DNA
DNA, Mitochondrial
Genetic Variation
Molecular Sequence Data
Rats
Repetitive Sequences, Nucleic Acid

Sequence Homology, Nucleic Acid

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Mitochondrial D-loop sequences are integrated in the rat nuclear genome.PMID 1942048Read

Native R-loops persist throughout the mouse mitochondrial DNA genome.Semantic proximity Read

Characterization of a novel plasmid-like element in Neurospora crassa derived mostly from the mitochondrial DNA.Semantic proximity Read

Mitochondrial DNA rearrangements, including partial duplications, occur in young and old rat tissues.Semantic proximity Read

Isolation of a genomic clone encoding the rat histone variant, H1d.Semantic proximity Read

Plasmids, Viruses, And Other Circular Elements In Rat GutSemantic proximity Read

Genome-wide reexamination of endogenous retroviruses in Rattus norvegicus.Semantic proximity Read

Conservation and losses of non-coding RNAs in avian genomes.Semantic proximity Read

A genome-wide circular RNA transcriptome in RatSemantic proximity Read