Multiple short direct repeats associated with single mtDNA deletions.

doi:10.1016/0925-4439(92)90106-w

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Article

Multiple short direct repeats associated with single mtDNA deletions.

Biochimica et biophysica acta - 25 Aug 1992

Larsson N G, Holme E

Abstract excerpt

We have sequenced the breakpoints of deleted mtDNA in muscle from four children with mitochondrial myopathy and multisystem mitochondrial disorders. The deletions were 4884, 6067, 7663 and 7150 base pairs (bp) in size and affected several protein and transfer RNA genes. The sequences needed for t...

Topics

Base Sequence
Cytochrome b Group
DNA, Mitochondrial
Electron Transport Complex IV
Humans
Kearns-Sayre Syndrome
Mitochondria, Muscle
Molecular Sequence Data
Muscular Diseases
Mutation
NADH Dehydrogenase
Proton-Translocating ATPases
Repetitive Sequences, Nucleic Acid
Sequence Alignment

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