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Article

Cellular Interaction of Integrin α3β1 with Laminin 5 Promotes Gap Junctional Communication

14 Dec 1998

Abstract excerpt

Wounding of skin activates epidermal cell migration over exposed dermal collagen and fibronectin and over laminin 5 secreted into the provisional basement membrane. Gap junctional intercellular communication (GJIC) has been proposed to integrate the individual motile cells into a synchronized colony. We found that outgrowths of human keratinocytes in wounds or epibole cultures display parallel changes in the...

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PMID: 9852164
DOI: 10.1083/jcb.143.6.1735

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