Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.

Journal of cell science - 1 Sept 2004

Sigle Randy O, Gil Susana G, Bhattacharya Mallar, Ryan Maureen C, Yang Tai-Mei, Brown Tod A, Boutaud Ariel, Miyashita Yuko, Olerud John, Carter William G

Abstract excerpt

In epidermal wounds, precursor laminin 5 (alpha3beta3gamma2) is deposited in the provisional basement membrane (PBM) before other BM components. Precursor laminin 5 contains G4/5 globular domains at the carboxyl terminus of the alpha3 chain. Here, the function of G4/5 was evaluated in deposition...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Basement Membrane
Share to Cell Adhesion
Share to Coculture Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fibronectins

Share to Keratinocytes

Share to Laminin

Share to Thrombin

Share to Wound Healing

Source

Identifiers

PMID: 15316072
DOI: 10.1242/jcs.01310

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15316072-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.PMID 15316072Read ↗

Biological function of laminin-5 and pathogenic impact of its deficiency.Semantic proximity Read ↗

Processing of Laminin α Chains Generates Peptides Involved in Wound Healing and Host DefenseSemantic proximity Read ↗

Proteolytic processing of the laminin alpha3 G domain mediates assembly of hemidesmosomes but has no role on keratinocyte migration.Semantic proximity Read ↗

Regulation of biological activity and matrix assembly of laminin-5 by COOH-terminal, LG4-5 domain of alpha3 chain.Semantic proximity Read ↗

Reduced expression of the epithelial adhesion ligand laminin 5 in the skin causes intradermal tissue separation.Semantic proximity Read ↗

Keratinocyte migration requires alpha2beta1 integrin-mediated interaction with the laminin 5 gamma2 chain.Semantic proximity Read ↗

Keratinocyte motility induced by TGF-beta1 is accompanied by dramatic changes in cellular interactions with laminin 5.Semantic proximity Read ↗

Laminin isoforms in development and disease.Semantic proximity Read ↗

Contributions of the LG modules and furin processing to laminin-2 functions.Semantic proximity Read ↗

A missense mutation (G1506E) in the adhesion G domain of laminin-5 causes mild junctional epidermolysis bullosa.Semantic proximity Read ↗

Functional Re-expression of laminin-5 in laminin-gamma2-deficient human keratinocytes modifies cell morphology, motility, and adhesion.Semantic proximity Read ↗

Laminins and human disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.