Article
Establishment and characterization of cell line LSV5 that retains the altered adhesive properties of human junctional epidermolysis bullosa keratinocytes.
Experimental cell research - 1 May 1996
Miquel C, Gagnoux-Palacios L, Durand-Clement M, Marinkovich P, Ortonne J P, Meneguzzi G
Abstract excerpt
Herlitz junctional epidermolysis bullosa (H-JEB) is characterized by hampered expression of the adhesion ligand laminin-5. Thus far, analysis of the processes underlying the epithelial-mesenchymal dysadhesion marking this disease has been limited by the reduced growth and adhesive capabilities of...
Topics
- 3T3 Cells
- Animals
- Basement Membrane
- Cell Adhesion
- Cell Adhesion Molecules
- Cell Division
- Cell Line, Transformed
- Cell Membrane
- Cell Movement
- Cell Transformation, Viral
- Epidermal Cells
- Epidermolysis Bullosa, Junctional
- Fluorescent Antibody Technique
- Humans
- Injections, Subcutaneous
- Isomerism
- Keratinocytes
- Laminin