Article
Gap junction-mediated cell-cell communication modulates mouse neural crest migration.
The Journal of cell biology - 14 Dec 1998
Huang G Y, Cooper E S, Waldo K, Kirby M L, Gilula N B, Lo C W
Abstract excerpt
Previous studies showed that conotruncal heart malformations can arise with the increase or decrease in alpha1 connexin function in neural crest cells. To elucidate the possible basis for the quantitative requirement for alpha1 connexin gap junctions in cardiac development, a neural crest outgrowth culture system was used to examine migration of neural crest cells derived from CMV43 transgenic embryos...
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