Article
Normal development of preimplantation mouse embryos deficient in gap junctional coupling.
Journal of cell science - 1 Aug 1997
De Sousa P A, Juneja S C, Caveney S, Houghton F D, Davies T C, Reaume A G, Rossant J, Kidder G M
Abstract excerpt
The connexin multigene family (13 characterized members in rodents) encodes the subunits of gap junction channels. Gap junctional intercellular coupling, established during compaction of the preimplantation mouse embryo, is assumed to be necessary for development of the blastocyst. One member of the connexin family, connexin43, has been shown to contribute to the gap junctions that form during compaction, yet...
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