Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.

doi:10.1083/jcb.143.6.1471

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Article

Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.

The Journal of cell biology - 14 Dec 1998

Gangwani L, Mikrut M, Galcheva-Gargova Z, Davis R J

Abstract excerpt

The zinc finger protein ZPR1 is present in the cytoplasm of quiescent mammalian cells and translocates to the nucleus upon treatment with mitogens, including epidermal growth factor (EGF). Homologues of ZPR1 were identified in yeast and mammals. These ZPR1 proteins bind to eukaryotic translation elongation factor-1alpha (eEF-1alpha). Studies of mammalian cells demonstrated that EGF treatment induces the...

Topics

Amino Acid Sequence
Animals
COS Cells
Carrier Proteins
Cell Cycle
Cell Division
Cell Line
Consensus Sequence
Fungal Proteins
G2 Phase
Gene Deletion
Genes, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Intracellular Signaling Peptides and Proteins

Mammals

Membrane Transport Proteins

Mice

Source

Open in PubMed Open full text

Identifiers

PMID: 9852145
DOI: 10.1083/jcb.143.6.1471
PMCID: PMC2132977

Genes

ZPR1
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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