Article
Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells.
The Journal of cell biology - 14 Dec 1998
Gangwani L, Mikrut M, Galcheva-Gargova Z, Davis R J
Abstract excerpt
The zinc finger protein ZPR1 is present in the cytoplasm of quiescent mammalian cells and translocates to the nucleus upon treatment with mitogens, including epidermal growth factor (EGF). Homologues of ZPR1 were identified in yeast and mammals. These ZPR1 proteins bind to eukaryotic translation elongation factor-1alpha (eEF-1alpha). Studies of mammalian cells demonstrated that EGF treatment induces the...
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