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Article

Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear export.

Molecular and cellular biology - 1 Oct 2002

Ansari Husam, Greco Giampaolo, Luban Jeremy

Abstract excerpt

The peptidyl-prolyl isomerase (PPIase) cyclophilin A (Cpr1p) is conserved from eubacteria to mammals, yet its biological function has resisted elucidation. Unable to identify a phenotype that is suggestive of Cpr1p's function in a cpr1Delta Saccharomyces cerevisiae strain, we screened for CPR1-dependent strains. In all cases, dependence was conferred by mutations in ZPR1, a gene encoding an essential zinc finger...

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Identifiers

PMID: 12242280
DOI: 10.1128/MCB.22.20.6993-7003.2002
PMCID: PMC139809

Genes

ZPR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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