Article
Evidences for an allelic variant of the human LC/CG receptor rather than a gene duplication: functional comparison of wild-type and variant receptors.
The Journal of clinical endocrinology and metabolism - 1 Dec 1998
Rodien P, Cetani F, Costagliola S, Tonacchera M, Duprez L, Minegishi T, Govaerts C, Vassart G
Abstract excerpt
Two different human LH receptor sequences have been published, differing by a six-base pair insertion encoding Leu-Gln at position 55-60. It has recently been proposed that this would reflect the existence of two LH receptor loci in the human genome. The present results demonstrate that both sequ...
Topics
- Alleles
- Asian People
- Gene Duplication
- Gene Frequency
- Genetic Variation
- Genotype
- Humans
- Japan
- Receptors, LH
- White People