Article
A splice variant of the human luteinizing hormone (LH) receptor modulates the expression of wild-type human LH receptor.
Molecular endocrinology (Baltimore, Md.) - 1 Jun 2004
Nakamura Kazuto, Yamashita Soichi, Omori Yuki, Minegishi Takashi
Abstract excerpt
We previously reported a splice variant form of human LH receptor [hLHR(exon 9)] that lacks exon 9, coding the N-terminal extracellular region close to the first transmembrane domain. Several recent studies suggest that G protein-coupled receptors are able to form dimerization or oligomerization of the receptor, suggesting an intermolecular interaction between hLHR(exon 9) and the wild-type LH receptor (hLHR)....
Topics
- Alternative Splicing
- Biotinylation
- Blotting, Western
- Cell Line
- Cyclic AMP
- Dimerization
- Electrophoresis, Polyacrylamide Gel
- Exons
- Genetic Vectors
- Glycosylation
- Humans