p53 gene mutations in rectal cancer associated with schistosomiasis japonica in Chinese patients.

doi:10.1016/s0304-3835(98)00154-2

Back to search

Article

p53 gene mutations in rectal cancer associated with schistosomiasis japonica in Chinese patients.

Cancer letters - 25 Sept 1998

Zhang R, Takahashi S, Orita S, Yoshida A, Maruyama H, Shirai T, Ohta N

Abstract excerpt

Mutations in p53 tumor suppressor gene were examined in 44 Chinese patients with rectal cancer, including 22 cases with advanced schistosomiasis japonica and 22 cases without schistosomiasis. In schistosomal rectal cancer (SRC), 13 mutations were found in 10 cases, which included 11 base-pair sub...

Topics

Aged
Carcinoma
China
Female
Genes, p53
Humans
Immunohistochemistry
Male
Middle Aged
Mutation
Polymerase Chain Reaction
Polymorphism, Single-Stranded Conformational
Rectal Neoplasms
Schistosomiasis japonica

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.