Article
Mutagenicity evaluation of Schistosoma spp. extracts by the umu-test and V79/HGPRT gene mutation assay.
Parasitology international - 1 Mar 2005
Osada Yoshio, Kumagai Takashi, Masuda Kyoko, Suzuki Tomoyuki, Kanazawa Tamotsu
Abstract excerpt
Schistosomiasis has been suspected of being a risk factor for various types of cancers for sometime, e.g., bladder cancer, colorectal cancer and hepatic cancer. Among them, the etiological relationship between urinary schistosomiasis and bladder cancer is now widely accepted. However, mechanisms of the carcinogenesis are still unclear. Here, we tested the mutagenicity of the parasite extracts by the umu-test and...
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